Fig. 3
Dynamics of the resistance alleles and selection coefficients estimations. Left panel represents the dynamics of the R1 allele (SR strain) frequency (± SD) over generations, in competition with the R2 allele (SRQ strain) in absence of insecticide (the dots of the 3 replicates are slightly offset for easier reading). The R1 allele dynamics predicted by the maximum likelihood fit of the reproduction-selection model is in red. Right panel represents the relative fitnesses along with their corresponding support limits (≈ 95% confidence intervals) of the different genotypes (R1R1 was used as the reference, hence fixed to 1), estimated through a maximum likelihood approach for the parameters’ values in the reproduction-selection model (see methods)