Fig. 1

Histological features of spleen section from healthy control rabbits and rabbits experimentally infected with Toxoplasma gondii. Images showing the H&E-stained spleen section at 100× (a, b). a Spleen section from healthy, uninfected rabbit. The structures of white pulp (WP) and red pulp (RP) were clearly identified with normal cell density. b Spleen section from a rabbit with acute T. gondii infection. The number and dimension of splenic nodule are increased, and more plasma cells are observed in the splenic cord (black triangle) of red pulp. Note that granulomas are present (big black arrow). Hemosiderin deposition (small black arrow) indicated red blood cell destruction. CA central arteriole. Scale bar = 100 μm