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Fig. 5 | Parasites & Vectors

Fig. 5

From: Proof-of-concept study for a long-acting formulation of ivermectin injected in cattle as a complementary malaria vector control tool

Fig. 5

Estimation of the dose–response relationship between ivermectin plasma concentrations and mosquito mortality when calves are injected with formulation A (solid red lines, red circles) or B (dotted blue lines, blue triangles). Lines are the estimated relationships following the log-logistic regression, while circles and triangles represent means of experimental data. Ivermectin-induced mortality is explored according to two scenarios A and B that would decrease the parasites’ transmission: A the mosquito dies within 7 days after an ivermectin blood meal (ivermectin blood meal is taken after the infectious one); B the mosquito dies within 13 days after the ivermectin blood meal (ivermectin blood meal is taken before the infectious one). Details of the two scenarios are given in the methods section and Fig. 1

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