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Table 2 Respiratory  complications, defined as respiratory signs that required additional treatment, in shelter dogs treated for heartworm infection. Italicized text shows time period of onset

From: Further variation of the adulticide protocol for the treatment of canine heartworm infection: can it be even shorter and cost less?

Dog #

Group

Days to M1

Doxycycline frequency

Treatment period 1

Treatment period 2

Treatment period 3

Problem

Treatmenta

Problem

Treatmenta

Problem

Treatmenta

125

A

19

Once daily

Cough

 

PTE

Prednisone

N/Ac

 

29

A

21

Once daily

Cough

Prednisone

Caval syndrome

Prednisone, CL

PTE

Prednisone, CL

82

B

22

Twice daily

Cough

Prednisone

Cough

 

Cough

 

85

B

23

Once daily

Cough

Prednisone

    

23

B

28

Once daily

Cough, IRE

   

Cough, IRE

Prednisone

144

B

30

Once daily

Cough, H, PHT

Prednisone, sildenafil

Cough

Prednisone, sildenafil

 

Sildenafil

71

B

34

Twice daily

Cough

Prednisone

    

27

B

46

Once daily

Cough

 

PTE

Prednisone, CL, O2

Cough

CL

39

B

49

Twice daily

Cough, IRE

Prednisone

IRE

   

36

C

60

Twice daily

    

IRE

Prednisone

47

D

86

Twice daily

Cough, IRE

Am-C

Cough

 

Cough

 
  1. H hemoptysis, IRE increased respiratory effort, M1 first melarsomine injection, O2 oxygen, PTE suspected pulmonary thromboembolism, PHT pulmonary hypertension, CL clopidogrel
  2. Am-C Amoxicillin-clavulanic acid for suspected bronchopneumonia
  3. aIn addition to standard treatment
  4. cMelarsomine discontinued after first melarsomine due to hepatopathy