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Table 2 Test prevalence of infection with D. immitis by diagnostic test and shelter location

From: Prevalence of canine heartworm infection in Queensland, Australia: comparison of diagnostic methods and investigation of factors associated with reduction in antigen detection

Diagnostic test

Brisbane dogs (n = 174)

Townsville dogs (n = 209)

All dogs (n = 383)

Prevalence difference (95% CI)a

P value b

Positive

Prevalence (95% CI)

Age (years), median (IQR)

Positive

Prevalence (95% CI)

Age (yrs), median (IQR)

Positive

Prevalence (95% CI)

Age (yrs), median (IQR)

Conventional antigen testing

2

1.1% (0.1, 4.1)

6.5 (5.0, 8.0)

46

22.0% (16.6, 28.2)

5.0 (2.0, 5.0)

48

12.5% (9.4, 16.3)

5.0 (2.0, 5.0)

20.9% (15.0, 26.7)

 < 0.001

Modified Knott’s test

2

1.1% (0.1, 4.1)

6.5 (5.0, 8.0)

35

16.7% (12.0, 22.5)

4.5 (2.0, 5.0)

37

9.7% (6.9, 13.1)

4.7 (2.3, 5.0)

15.6% (10.3, 20.9)

 < 0.001

Conventional antigen testing and modified Knott’s test combined

2

1.1% (0.1, 4.1)

6.5 (5.0, 8.0)

54

25.8% (20.0, 32.3)

3.0 (2.0–5.0)

56

14.6% (11.2, 18.6)

4.5 (2.0, 5.0)

24.7% (18.5, 30.8)

 < 0.001

Antigen testing after heat treatment

3

1.7% (0.1, 5.0)

5.0 (2.2, 8.0)

67

32.1% (25.8, 38.8)

4 (2.0, 5.0)

70

18.3% (14.5, 22.5)

4.0 (2.0, 5.0)

30.3% (23.7, 36.9)

 < 0.001

  1. aEstimated difference in prevalence between Brisbane and Townsville
  2. bP value for two-sample test of proportions, with Bonferroni correction