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Fig. 1 | Parasites & Vectors

Fig. 1

From: Leishmania tarentolae: a vaccine platform to target dendritic cells and a surrogate pathogen for next generation vaccine research in leishmaniases and viral infections

Fig. 1

Schematic representation of the cutis of a mammal and a lymph node. A Leishmania-infected Phlebotominae sand fly is also represented (1). A dendritic cell (DC) is represented during the process of phagocytosis of a Leishmania promastigote (2), the transformation of the promastigote into the amastigote stage (3) and then the migration of the infected DC towards the lymph node (4). Inside the lymph node, DCs present the antigens to CD4+ T cells. A neutrophil is also shown as these cells play a role in the first phases of mammalian infection by Leishmania spp (5)

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