Skip to main content
Fig. 4 | Parasites & Vectors

Fig. 4

From: Proteomic analysis of exosome-like vesicles from Fasciola gigantica adult worm provides support for new vaccine targets against fascioliasis

Fig. 4

EVs stimulate protective immunity against F. gigantica metacercariae challenge in ICR mice. Female ICR mice, n = 8 per group, were vaccinated (intraperitoneally [I.P.]) with 15k EVs, 100k EVs, ESPs, rFg-HSP70 or PBS in alum adjuvant prior to challenge with 15 F. gigantica metacercariae. Shown are representative pictures of macroscopic pathological lesions in livers of infected mice recovered at 4 weeks post-infection. Groups: Alum:ESP, ESP-immunized and infected group; Alum:15k EVs, 15k EV-immunized and infected group; Alum:100k EVs, 100k EV-immunized and infected group; Alum:HSP70, rFg-HSP70-immunized and infected group; Alum:PBS, adjuvant-infected control group; Blank, non-immunized and non-infected group. ESPs, Excretory/secretory products

Back to article page

Parasites & Vectors

ISSN: 1756-3305

Contact us