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Fig. 6 | Parasites & Vectors

Fig. 6

From: Proteomic analysis of exosome-like vesicles from Fasciola gigantica adult worm provides support for new vaccine targets against fascioliasis

Fig. 6

Serum IgG, IgG1, IgG2a levels in vaccinated ICR mouse. Serum IgG (a–c), IgG1(d–f) and IgG2a (g–i) levels were measured from the vaccinated groups (mice immunized with 15k EVs, 100k EVs, ESPs and PBS in alum adjuvant prior to challenge with 15 F. gigantica metacercariae) and non-immunized and uninfected group. Mean IgG (a–c), IgG1 (d–f) and IgG2a (g–i) levels were measured against ESPs (a, d, g), 15k EVs (b, e, h) and 100k EVs (c, f, i) by indirect enzyme-linked immunosorbent assay. Results represent the mean absorbance measured at 450 nm for each group. Asterisks indicate level of significance between groups: *P < 0.05, **P < 0.01, ***P < 0.001. NS, Non-significant

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