Table 3 Viability percentage of Leishmania major promastigotes in different concentrations of larval products
Time points (hours) | 24Â h | 96Â h | |||||
|---|---|---|---|---|---|---|---|
Groups | Concentration (ug/ml) | Mean ± SD | Mean differencea (95% CI) NC group | Statistical analysisb | Mean ± SD | Mean differencea (95% CI) NC group | Statistical analysisb |
Larval products | 75 | 85.2 ± 7.7 | − 13.8 (− 18.6 to − 9.1) | F(10, 83) = 310.83 P < 0.0001* | 46.8 ± 5.2 | − 52.0 (− 57.8 to − 46.1) | F(10, 83) = 530.50 P < 0.0001 |
150 | 80.9 ± 5.8 | − 18.2 (− 22.9 to − 13.5) | 38.5 ± 4.9 | − 60.3 (− 66.2 to − 54.5) | |||
300 | 72.6 ± 6.1 | − 26.5 (− 31.2 to − 21.7) | 30.0 ± 4.2 | − 68.8 (− 74.7 to − 63.0) | |||
450 | 61.5 ± 3.8 | − 37.6 (− 42.3 to − 32.9) | 21.3 ± 3.2 | − 77.5 (− 83.3 to − 71.6) | |||
600 | 53.8 ± 3.9 | − 45.2 (− 49.9 to − 40.5) | 17.1 ± 3.1 | − 81.7 (− 87.6 to − 75.9) | |||
750 | 47.0 ± 4.1 | − 52.1 (− 56.8 to − 47.4) | 11.3 ± 1.9 | − 87.5 (− 93.3 to − 81.6) | |||
Glucantime | 25 | 71.5 ± 6.1 | − 27.6 (− 32.3 to − 22.9) | F(10, 83) = 310.83 P < 0.0001 | 20.7 ± 2.6 | − 78.1 (− 83.9 to − 72.2) | F(10, 83) = 530.50 P < 0.0001 |
50 | 59.6 ± 5.6 | − 39.5 (− 44.2 to − 34.7) | 14.0 ± 2.9 | − 84.8 (− 90.7 to − 79.0) | |||
100 | 48.3 ± 4.7 | − 50.7 (− 55.4 to − 46.0) | 11.8 ± 1.4 | − 87.0 (− 92.8 to − 81.1) | |||
250 | 39.0 ± 4.1 | − 60.1 (− 64.8 to − 55.4) | 10.3 ± 1.5 | − 88.5 (− 94.3 to − 82.6) | |||
NC group | 0 | 99.1 ± 6.8 | Not applicable | Not applicable | 98.8 ± 8.9 | Not applicable | Not applicable |