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Table 9 Comparison of the lesion size (mm²) before, immediately after and 4 weeks after the intervention in treatment groups

From: The therapeutic effect of larval saliva and hemolymph of Lucilia sericata on the treatment of Leishmania major lesion in BALB/c mice946

Study group

Mean ± SD

Mean differencea (95% CI) G7 groupa

Statistical analysisb

Before intervention (week 5)

Immediately after intervention (week 9)

4 weeks after the intervention (week 13)

G1

14.7 ± 2.5

3.8 ± 1.2

5.5 ± 1.3

− 19.1 (− 25.6 to − 12.5)

F (7, 38) =8.54, P = 0.001*

G2

14.5 ± 2.6

23.5 ± 4.0

23.9 ± 4.2

0.63 (− 3.9 to 2.5)

F (7, 38) =8.54, P = 0.811

G3

13.9 ± 2.8

20.9 ± 2.5

20.9 ± 2.7

− 1.9 (− 4.5 to 3.5)

F (7, 38) =8.54, P = 0.811

G4

14.2 ± 2.5

3.1 ± 1.1

3.0 ± 1.2

− 19.7(− 26.3 to − 13.1)

F (7, 38) =8.54, P = 0.001

G5

14.0 ± 2.3

9.9 ± 2.1

10.9 ± 2.3

− 12.9 (− 15.5 to 2.3)

F (7, 38) =8.54, P = 0.811

G6

14.1 ± 2.9

8.2 ± 1.8

7.7 ± 1.9

− 14.6 (− 19.6 to − 10.5)

F (7, 38) =8.54, P = 0.001

G7

12.8 ± 2.6

22.9 ± 2.8

24.0 ± 4.4

Not applicable

Not applicable

G8

13.1 ± 2.3

11.7 ± 1.9

4.7 ± 1.4

− 20.0 (− 24.6 to − 17.5)

F (7, 38) =8.54, P = 0.001

  1. aMean difference treatment group compared to G7 (no treatment group) at week 9
  2. bCalculated based on ANOVA-ANCOVA
  3. *Statistically significant < 0.05
  4. G7 negative control or no treatment group