Table 2 Prevalence of cytokine production, calculated as the percentage of dogs from each group producing one cytokine, divided according to groups
From: Interaction between Wolbachia pipientis and Leishmania infantum in heartworm infected dogs
Groups | qPCR Wolbachia | Cytochine production | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n dogs Pos (%) | TNFα | IFNγ | IL-10 | IL-4 | IL-6 | ||||||
Concentration (pg/ml) | Prevalence | Concentration (pg/ml) | Prevalence | Concentration (pg/ml) | Prevalence | Concentration (pg/ml) | Prevalence | Concentration (pg/ml) | Prevalence | ||
min–mean–max | n dogs Pos (%; 95%CI) | min–mean–max | n dogs Pos (%; 95%CI) | n dogs Pos (%; 95%CI) | min–mean–max | n dogs Pos (%; 95%CI) | min–mean–max | n dogs Pos (%;95%CI) | |||
G1 (n = 14) | 12 (85.7)6,7,8 | 44.8–246.5–649.4 | 4 (28.6; 0.084–0.581)1,8 | 3.6–88.2–475 | 9 (64.3; 0.351–0.872)a,2 | 5.97–1809.5–4120 | 10 (71.4; 0.419–0.916)1,3 | 77.2 | 1 (7.1; 0.002–0.339)2,3,6 | 3.01–123.5 -392.6 | 5 (35.7; 0.128–0.649)7 |
G2 (n = 14) | 14 (100) | 2.27 – 65.1 -172.9 | 6 (42.8; 0.177–0.711) | 13.3–105.4–265.1 | 7 (50; 0.230–0.770)b | 19.1–507.8–1440 | 7 (50; 0.230–0.770) | 501.1–2794.5–5739.5 | 4 (28.5; 0.084–0.581) | 5.05–30.2–105 | 7 (50; 0.230–0.770) |
G3 (n = 14) | N/A | – | – | 0.65–97.23–617.6 | 7 (50; 0.230–0.770)b | 50.4–677.4–2644.8 | 6 (42.8; 0.177–0.711) | 62.5–254.9–480.4 | 4 (28.5; 0.084–0.581) | 6.1–29.7–67.2 | 7 (5 0:0.230–0.770) |
G4 (n = 14) | N/A | 8.1- 13.3–18.6 | 2 (14.3; 0.018–0.428)4 | 3.6–3.7–23.7 | 2 (14.2; 0.018–0.428)a,b,4 | 81.9–863.8–3320 | 8 (57.1; 0.289–0.823)4,5 | 62.5–111.7–160.9 | 2 (14.3; 0.018–0.428)5 | 5.05–13.9–22.3 | 5 (35.7; 0.128–0.649) |
Total (n = 56) | 26 (46.4) | – | 12 (21.4; 0.116–0.344) | – | 25 (44.6; 0.313–0.585) | – | 31 (55.4; 0.415–0.687) | – | 11 (19.6; 0.102–0.324) | – | 24 (42.9; 0.297–0.568) |