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Fig. 4 | Parasites & Vectors

Fig. 4

From: Genome-wide liver transcriptomic profiling of a malaria mouse model reveals disturbed immune and metabolic responses

Fig. 4

Coexpression network analysis of the dual RNA sequencing data of the host and P. yoelii. a Enriched genes of P. yoelii in modules (colors along X-axis) that are highly related to infection/control conditions. Low correlation coefficients of modules are shown in blue, and high correlation coefficients are shown in yellow (see scale at upper right). b Gene coexpression network of the pink module. The top 300 gene pairs ranked by their connectivity value are displayed. The purple dots represent genes of P. yoelii, and the green dots represent coexpressed host genes. The color shade and width of the lines between genes represent the connectivity. c Overlapping GO terms and KEGG pathways with FDR < 0.05 in five highly infection-related modules. The size of the dots represents -log10(FDR) and transparency represents log2(fold enrichment) of terms. FDR, False detection rate; FE, fold enrichment

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