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Fig. 5 | Parasites & Vectors

Fig. 5

From: β-Glucan alleviates goal-directed behavioral deficits in mice infected with Toxoplasma gondii

Fig. 5

β-Glucan administration restrained the hyperactivation of astrocyte the PFC of chronic T. gondii Wh6-infected mice. Immunofluorescent staining was performed to detect the number and morphology of astrocytes in the PFC of chronic T. gondii Wh6-infected mice. a Representative immunofluorescence staining of GFAP-positive (GFAP+) astrocytes in the PFC of mice (scale bar: 50 μm). Area in box in each image is enlarged in the respective inset in each image, marked with a solid line (scale bar: 10 μm). Solidity and circularity are used to describe the morphology of astrocyte (n = 3 mice, 9–12 cells per mouse). b Quantification of GFAP+ astrocyte in the PFC. c Solidity of GFAP+ astrocyte in the PFC. d Circularity of GFAP+ astrocyte in the PFC. Asterisks indicate a statistically significant difference at *** P < 0.001, according to one-way ANOVA followed by Tukey’s test for multiple comparisons. GFAP, Glial fibrillary acidic protein

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