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Table 2 Clinical signs by treatment group (control group, 1× treatment group; 3× treatment group): number of animals affected and total number of observations Days 0–84

From: Safety of Simparica Trio® (sarolaner, pyrantel, moxidectin) in heartworm-infected dogs

Clinical sign

Control

# Dogs

# Obs

# Dogs

# Obs

# Dogs

# Obs

Abnormal stools

2

3

4

23

7

23

Decreased appetite

0

0

4

5

5

6

Fever (> 104 °F/40 °C)

0

0

1

1

1

1

Emesis

3

3

2

3

4

7