From: Safety of Simparica Trio® (sarolaner, pyrantel, moxidectin) in heartworm-infected dogs
Clinical sign | Control | 1× | 3× | |||
---|---|---|---|---|---|---|
# Dogs | # Obs | # Dogs | # Obs | # Dogs | # Obs | |
Abnormal stools | 2 | 3 | 4 | 23 | 7 | 23 |
Decreased appetite | 0 | 0 | 4 | 5 | 5 | 6 |
Fever (> 104 °F/40 °C) | 0 | 0 | 1 | 1 | 1 | 1 |
Emesis | 3 | 3 | 2 | 3 | 4 | 7 |