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Table 3 Least square means microfilariae count (counts/ml) for post-treatment time points

From: Safety of Simparica Trio® (sarolaner, pyrantel, moxidectin) in heartworm-infected dogs

Study day

1

3

7

14

21

28

35

56

63

83

Control

12,289

20,149

24,440

27,462

25,695

28,659

26,342

23,717

22,519

21,622

3711*

2503*

644*

179*

212*

104*

80*

147*

265*

24*

% Reduction

69.8

87.6

97.4

99.3

99.2

99.6

99.7

99.4

98.8

99.9

1803*

1833*

1494*

359*

221*

146*

110*

112*

205*

3*

% Reduction

85.3

90.9

93.9

98.7

99.1

99.5

99.6

99.5

99.1

 > 99.9

  1. *Significant at two-sided alpha = 0.10 (P ≤ 0.10)