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Table 4 Significant TreeSAAP z scores denoting amino acid physicochemical property alterations across Schistosoma japonicum tetraspanin proteins; SjTSP-2, SjTSP-8 and SjTSP-23

From: Evolution of tetraspanin antigens in the zoonotic Asian blood fluke Schistosoma japonicum

Tetraspanin (TSP)

Amino acid physicochemical properties

Magnitude category (z scores)

5

6

7

8

SjTSP-2

Isoelectric point

  

2.219 *

1.92 *

Mean RMS fluctuation displacement

  

−2.18 *

 

Partial specific volume

 

2.041 *

  

Chromatographic index

 

−1.911 *

  

Hydropathy

−1.679 *

   

Composition

−1.739 *

   

SjTSP-8

Power to be at the N-terminal

   

2.385 **

Refractive index

  

7.047 ***

 

Composition

 

7.677 ***

  

Equilibrium constant (ionisation of COOH)

 

2.349 **

  

Mean RMS fluctuation displacement

 

2.301 *

  

Average number of surrounding residues

 

2.228 *

  

Hydropathy

 

2.210 *

  

Compressibility

5.025 ***

   

Bulkiness

3.139 ***

   

Power to be at the middle of α-helix

2.036 *

   

SjTSP-23

Polar requirement

  

3.238 ***

 

Refractive index

  

2.575 **

 

Coil tendencies

  

1.978 *

 

Composition

 

2.640 **

  

Compressibility

1.674 *

2.407 **

  

Total non-bonded energy

 

1.862 *

  
  1. Magnitude categories denoting ‘radical’ or ‘substantial’ property changes (5–8) are shown; *P < 0.05, **P < 0.01, ***P < 0.001