Genetic diversity of transmission-blocking vaccine candidates Pvs25 and Pvs28 in Plasmodium vivax isolates from Yunnan Province, China

Table 1 Amino acid substitutions of Pvs25 from Yunnan P. vivax isolates

Haplotypes (number)	EGF-1	EGF-2	EGF-3	EGF-3
	35	97	130	131
Sal-I	L	E	I	Q
Pvs25-I (n = 15)	•	•	T	•
Pvs25-II (n = 8)	•	•	T	K
Pvs25-III (n = 5)	•	Q	T	•
Pvs25-IV (n = 1)	•	Q	T	K
Pvs25-V (n = 1)	M	•	T	K

EGF, epidermal growth factor-like domain. • indicates identical amino acid residues compared to the Salvador I strain.

ISSN: 1756-3305