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Table 6 Percentage of households free of fleas or ticks

From: A randomized, blinded, controlled and multi-centered field study comparing the efficacy and safety of Bravecto™ (fluralaner) against Frontline™ (fipronil) in flea- and tick-infested dogs

 

Bravecto™ (fluralaner)

Frontline™ (fipronil)

p value

Lower 97.5% 1-sided C.I.a

Fleas

    

 Week 2

89.57%

62.30%

<0.0001

0.1498

 Week 4

94.87%

63.93%

<0.0001

0.1916

 Week 8

95.65%

70.49%

<0.0001

0.1416

 Week 12

97.39%

81.97%

<0.0001

0.0586

Ticks

    

 Week 2

97.67%

89.47%

0.0006

-0.0575

 Week 4

97.67%

84.21%

0.0001

-0.0175

 Week 8

97.67%

94.74%

0.0024

-0.0953

 Week 12

100.0%

100.0%

n/ab

n/ab

  1. aResult greater than -0.15 required to declare significant non-inferiority. Result greater than 0 required to declare significant one-sided superiority with α = 0.025.
  2. bNo statistical test as all households were free of ticks at week 12.
  3. n/a: not applicable.