New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel

Table 5 The effect of covariates on average egg reduction rates among children infected with schistosomes following treatment with praziquantel

Covariates	Levels	ERR (95 % CI)
Schistosoma haematobium dataset
(Baseline)	Côte d’Ivoire; male; younger SAC; 40 mg/kg; 21 days follow-up	99.7 % (97.4 %, 100 %)
Country	Kenya^a	99.8 % (98.8 %, 100 %)
Sex	Female	99.7 % (95.7 %, 100 %)
Age group	Older SAC	95.9 % (85.8 %, 98.8 %)
Schistosoma mansoni dataset
(Baseline)	Côte d’Ivoire; male; younger SAC; 40 mg/kg; 21 days follow-up	95.4 % (83.1 %, 98.8 %)
Country	Uganda	85.3 % (73.5 %, 91.8 %)
Dose	60 mg/kg	98.5 % (90.8 %, 99.8 %)
Sex	Female	93.2 % (74.1 %, 98.2 %)
Age group	Pre-SAC	95.3 % (80.9 %, 98.8 %)
	Older SAC	96.6 % (85.8 %, 99.2 %)
Follow-up time	28 days	84.9 % (76.7 %, 90.1 %)
	42 days	73.6 % (53.2 %, 85.1 %)

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