Table 3 Validation of homology models of L. donovani Inl-A-like proteins
From: Identification of internalin-A-like virulent proteins in Leishmania donovani
L. donovani Inl-A-like proteins | E9B7L9 | E9BMT7 | E9BUL5 | |
|---|---|---|---|---|
Predicted Inl-A-like Region | 212–573 | 394–757 | 386–782 | |
Sequence similarity index | ||||
 Whole Sequence Identity with Inl-A (UniProt ID: PODJMO) | 18 % | 15 % | 16.8 % | |
 LRR Region Sequence Identity with Inl-A (UniProt ID: PODJMO) | 21 % | 20 % | 22 % | |
 LRR Region Sequence Similarity with Inl-A (UniProt ID: PODJMO) | 41.7 % | 41.2 % | 33.4 % | |
Structure Similarity Index | Â | |||
 Root Mean Square Deviation (RMSD) [Å] with Inl-A (PDB ID: 1O6S, chain A) | 1.2 | 1 | 1.5 | |
Stereo-chemical Evaluation | ||||
 Ramachandran Plot [47] | Favored | 320 (88.9 %) | 319 (88.1 %) | 334 (84.6 %) |
Allowed | 37 (10.3Â %) | 39 (10.8Â %) | 53 (13.4Â %) | |
Outlier | 3 (0.8Â %) | 4 (1.1Â %) | 8 (2.0Â %) | |
Passed (93.65 % of the residues had an averaged 3D–1D score > = 0.2) | Passed (91.21 % of the residues had an averaged 3D–1D score > = 0.2) | Passed (88.92 % of the residues had an averaged 3D–1D score > = 0.2) | ||