Fig. 2From: Nitric oxide and cytokine production by glial cells exposed in vitro to neuropathogenic schistosome Trichobilharzia regenti NO production by murine primary astrocyte and microglia cultures exposed to Trichobilharzia regenti derived stimulants. Griess assay was used to measure concentration of nitrite (NO degradation product) in cell supernatants 48 h after the cells were exposed to the stimulants. Key: −, non-stimulated group (a negative control); +, LPS - stimulated group (a positive control); LS, living schistosomulum-like stages stimulated group; HSF, soluble fraction of LS homogenate stimulated group; CB1.1, recombinant T. regenti cathepsin B1.1 stimulated group; CB2, recombinant T. regenti cathepsin B2 stimulated group. Data are shown as the mean ± standard error of the mean (SEM) of five independent experiments. Significant differences in comparisons with the non-stimulated group are marked by asterisks: *P < 0.05, **P < 0.01, ***P < 0.001 (Dunn’s multiple comparisons test)Back to article page