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Table 3 Similarity ratios produced by pairwise alignment of LmlRab with Leishmania strains ortholog sequences

From: Leishmania major large RAB GTPase is highly immunogenic in individuals immune to cutaneous and visceral leishmaniasis

Leishmania strain

Chromosome/Gene ID

Genomic coordinates

Producta

Similarity %

Similarity %

Similarity %

L. major HV P25 (Tunisia)

N-ter

C-Ter

AY962589.1

AY962589.1

AY962589.1

N (%)

P (%)

N (%)

P (%)

N (%)

P (%)

L. major Friedlin

LmjF.31.0860

315900–317732 (–)

ras-like small GTPases, putative

99.60

98.90

99.5

98.9

99.6

98.8

L. major strain SD 75.1

JH605118.1

298109–299941 (–)

not yet annotated

99.60

98.90

99.5

98.8

99.5

98.9

L. major strain LV39c5

KB217892.1

1129713–1131545

not yet annotated

99.50

98.70

99.5

98.9

99.6

98.6

L. infantum JPCM5

LinJ.31.0890

322703–324532 (–)

ras-like small GTPases, putative

94.40

91.00

94.00

94.5

93.0

89.3

L. donovani BPK282A1

LdBPK_310890.1

329426–331255 (–)

not yet annotated

93.30

90.80

94.2

95.1

92.6

88.6

L. tropica L590

KE147396.1

108776–110605 (–)

not yet annotated

94.30

90.70

90.4

94.0

87.1

89.0

L. tropica L590

KE147396.1

100399–102228 (–)

not yet annotated

94.30

90.70

95.4

95.1

93.6

89.3

L. mexicana U1103

LmxM.30.0860

324259–326091 (–)

ras-like small GTPases, putative

93.10

90.50

96.2

90.2

88.0

79.4

L. amazonensis M2269

KE390271.1

700–2532

not yet annotated

94.20

90.50

90.4

89.6

87.1

78.3

L. aethiopica L147

AUMB01001544.1

10483–12315

not yet annotated

88.70

82.70

95.4

93.4

93.8

89.5

L. aethiopica L147

AUMB01001560.1

101–1933

not yet annotated

88.10

81.70

95.4

93.4

93.8

89.5

L. braziliensis M2904

LbrM.31.1020

360616–362445 (–)

ras-like small GTPases, putative

74.50

63.80

78.1

74.3

72.9

59.3

L. braziliensis M2903

LbrM2903_31_1140

408882–410711 (–)

ras-like small GTPases, putative

74.40

63.70

78.3

74.3

72.9

59.3

  1. aAccording to TriTrypDB release 24 (15/04/2015) www.tritrypdb.org
  2. For each of the selected Leishmania strains, the chromosome (or gene ID if chromosome were not assembled yet), the genomic coordinates and the gene product as described in the TriTrypDB server (Release 24 of 15/04/2015) is provided. Similarity ratios were drawn from pairwise alignments of both nucleic (columns noted “N”) and peptidic (columns noted “P”) sequences, regarding the entire gene sequence (column named “L. major HV P25 (Tunisia)”), the so called N-terminal region ranging from residue 1 to 183 (column named “N Ter”) and the so called C-terminal region ranging from residue 184 to 611 (column named “C Ter”)