Table 1 Experimental model of allergic sensitization and anaphylactic response in BALB/c mice with Anisakis pegreffii or Pseudoterranova decipiens
From: Allergenic activity of Pseudoterranova decipiens (Nematoda: Anisakidae) in BALB/c mice
Mice group (5 mice per group) | Infection | Re-infection | Challenge | Evaluation of allergic reactions 60 min after the last challenge | Evaluation of the immune responses 24 h after the last challenge |
|---|---|---|---|---|---|
Anisakis pegreffii | |||||
1 Ap | 2 L3 per os | 2 L3 per os | 5 mg CWE per os | yes | yes |
2 Ap | 2 L3 i.p. | 2 L3 i.p. | 5 mg CWE per os | yes | yes |
Inoculation | Challenge | Challenge | |||
3 Ap | 700 μg CWE per os | 700 μg CWE per os | 5 mg CWE per os | yes | yes |
4 Ap | PBS per os | PBS per os | PBS per os | yes | yes |
Week p.i. | 0 | 8 | 12 | 12 | 12 |
Pseudoterranova decipiens | |||||
Infection | Re-infection | Challenge | |||
1 Pd | 2 L3 i.p. | 2 L3 i.p. | 5 mg CWE per os | yes | yes |
Inoculation | Challenge | Challenge | |||
2 Pd | 700 μg CWE per os | 700 μg CWE per os | 5 mg CWE per os | yes | yes |
3 Pd | PBS per os | PBS per os | PBS per os | yes | yes |
Week p.i. | 0 | 8 | 12 | 12 | 12 |