Efficacy of fluralaner (Bravecto™ chewable tablets) for the treatment of naturally acquired Linognathus setosus infestations on dogs

Table 1 Mean lice counts and efficacy (%) after a single oral administration of fluralaner or topical administration of permethrin to dogs naturally infested with lice L. setosus

	Study day	Dogs^a	Count range (n)	Geometric mean lice count	Efficacy (%)	P-value^c
Fluralaner	0	14	1–115	8.0	–	–
	1	14	0–38	1.6	85.7	0.0088
	7	14	0–3	0.3	96.8	< 0.0001
	28	13	0–0	0.0	100	< 0.0001
	84	11	0–0	0.0	100	< 0.0001
Permethrin	0	10	1–36	10.2	–	–
	1	10	0–25	3.3	67.5	0.0854
	7	9^b	0–7	1.0	90.3	0.0014
	28	8^b	0–1	0.1	99.1	< 0.0001

^aNumber of dogs presented to visit
^bDog withdrawn from the study due to insufficient permethrin treatment effect against L. setosus
^cTwo-sided two-sample t-test (α = 0.05)

ISSN: 1756-3305