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Table 2 Lice-free dogs and households after a single oral administration of fluralaner or topical administration of permethrin to dogs naturally infested with lice L. setosus

From: Efficacy of fluralaner (Bravecto™ chewable tablets) for the treatment of naturally acquired Linognathus setosus infestations on dogs

Study day

Lice-free dogs

Lice-free households

Fluralaner (%)

Permethrin (%)

Lower 97.5% CLa

P-valueb

Fluralaner (%)

Permethrin (%)

Lower 97.5% CLa

P-valueb

1

64

20.0

0.0417

0.0019

62

13

0.0554

0.0020

7

79

44.4

-0.0502

0.0070

77

43

-0.0858

0.0121

28

100

87.5

-0.1311

0.0177

100

83

-0.1182

0.0147

84

100

na

100

na

  1. Abbreviation: na not applicable
  2. aConfidence limits based upon the Farrington-Manning test of non-inferiority for the risk difference. Results > -0.15 for significant non-inferiority and results > 0 for significant one-sided superiority with α = 0.025
  3. bFarrington-Manning test of non-inferiority for the risk difference