Evaluation of oral fluralaner (Bravecto®) for efficacy against nymphs of Amblyomma americanum and Rhipicephalus sanguineus (sensu lato)

Table 4 Percent efficacy of fluralaner based on all live and live-fed Rhipicephalus sanguineus (sensu lato) nymphs from control and treated dogs (Experiment 2). Each group had 10 dogs

Infestation day	Count^a day	Control		Fluralaner						Efficacy
Infestation day	Count^a day	GM (L)	GM (LF)	GM (L)	GM (LF)	t-value (L)	t-value (LF)	P-value (L)	P-value (LF)	% (L)	% (LF)
− 1	2	21.8	20.6	0.0	0.0	t_(9.0) = 39.1	t_(18.0-) = 39.0	< 0.001	< 0.001	100	100
6	9	13.4	11.9	0.8	0.0	t_(9.0) = 7.6	t_(18.0) = 10.8	< 0.001	< 0.001	94.0	100
28	31	10.0	7.5	2.3	0.0	t_(9.0) = 4.3	t_(18.0) = = 11.1	0.002	< 0.001	76.8	100
56	59	13.0	9.8	1.8	0.0	t_(18.0) = 6.9	t_(18.0) = 14.3	< 0.001	< 0.001	86.3	100
84	87	13.0	10.4	1.0	0.0	t_(18.0) = 7.1	t_(18.0) = 21.4	< 0.001	< 0.001	91.9	100

Abbreviations: GM, geometric mean; L, all live (attached and engorged, attached and not engorged, free and engorged, and free and not engorged); LF, live-fed (attached and engorged, attached and not engorged, and free and engorged)
^a48 h count data (Days 1, 8, 30, 58 and 86) are not included because adequacy of infestations on control dogs were not achieved

ISSN: 1756-3305