Table 1 Characteristics of the populations included in the analysis

Number of patients

38

16

G6PD deficient

No

Yes

Males, %

42.1

100

P. falciparum infected, %

100

69

Number treated with 0.25 mg/kg primaquine

18

10

Number treated with 0.4 mg/kg primaquine

20

6

Age in years, median (range)

9.5 (2–14)

24.5 (13–44)

Weight in kg, median (range)

23.3 (12.1–43.5)

55.4 (29.9–76.4)

Baseline Hb in g/dl, median (range)

11.7 (9.3–13.8)

13.1 (12–15.4)

Number of pharmacokinetic samples

228

97

Pharmacokinetic data BLQ, %

14.2

25.2

Number of Hb samples

226

199

CYP2D6 AS distribution, n (%)

 0

1 (2.63)

0 (0)

 0.5

4 (10.5)

4 (25)

 1

6 (15.8)

1 (6.25)

 1.5

13 (34.2)

7 (43.75)

 2

7 (18.4)

3 (18.75)

 3

3 (7.89)

0 (0)

 Missing

4 (10.5)

1 (6.25)