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Table 1 Candidates that elicited significant oviposition stimulation or deterrence in laboratory assays and level of validation

From: Semiochemical oviposition cues to control Aedes aegypti gravid females: state of the art and proposed framework for their validation

Candidate

Effect on oviposition

OAI

Dosea

Validation in field experiments

References

Crude semiochemicals of plant origin

 Infusions

  Graminea (Panicum maximum) infusion

Stimulation

NM

10%

Yes

[57]

  Bermuda grass (Cynodon dactylon) infusion

Stimulation

0.5

5% and 10% infusion

NT

[62]

  Cashew leaves (Anacardium occidentale) infusion

Stimulation

NM

50%

NT

[65]

  Tea infusion

Stimulation

NM

3 teabags or 4 capsules in 8 l of water

NT

[35]

  Bamboo leaf (Arundinaria gigantea) and white oak leaf (Quercus alba) infusion

Stimulation

NM

50%

NT

[88]

  Neem seed kernel (Azadirachta indica) infusion

Deterrence

−0.6

10%

NT

[62]

  Dried tobacco leaves (Nicotiana spp.) infusion

Deterrence

−0.7

10%

NT

[62]

 Extracts

  Beetroot (Beta vulgaris) peel

Stimulation

0.7

10 g in 600 ml of water

Yes

[33]

  Sweet wormwood (Artemisia annua) extracts

Deterrence

−0.94

500 ppm

NT

[73]

 Essential oils

  Peppermint oil, basil oil, rosemary oil, citronella oil and celery seed oil

Deterrence

−0.22 to −0.95

10%

NT

[68]

Crude semiochemicals of larval origin

 Larvae infusion

Stimulation

0.5

100 larvae/100 ml

Yes

[41, 61]

 Larvae infusion

Deterrence

−0.45

5 larvae/2 ml

 

[42]

Chemical compounds

 n-Heneicosane

Stimulation

0.09

10 ppm

Yes

[30, 64, 87]

 Geosmin

Stimulation

0.2

0.01%

Yes

[33]

 Tetradecanoic acid

Stimulation

NM

10 ng

Yes, in blend with nonanoic acid and tetradecanoic acid methyl ester

[88]

 Nonanoic acid

Stimulation

NM

100 ng

Yes, in blend with tetradecanoic acid and tetradecanoic acid methyl ester

[88]

 Tetradecanoic acid methyl ester

Stimulation

NM

10 ng

Yes, in blend with tetradecanoic acid and nonanoic acid

[88]

 Nonanal

Stimulation

NM

NM

Yes

[11, 12, 31]

 Dodecanoic acid

Stimulation

0.54

100 ppm

NT

[47]

 Z-9-Hexadecenoic acid

Stimulation

0.55

10 and 100 ppm

NT

[47]

 Caproic acid

Stimulation

0.32

1 ppm

NT

[46]

 Pentadecanoic acid

Stimulation

0.38

10 ppm

NT

[61]

 Myristoleic acid

Deterrence

−0.7

100 ppm

NT

[61]

 Skatole

Stimulation

0.41

500 ppm

NT

[64]

 Skatole

Deterrence

NM

100 μg/l

NT

[76]

 p-Cresol

Stimulation

0.23

100 ppm

NT

[64]

 p-Cresol

Deterrence

−0.4 to −1

10–8 to 103 ppm

NT

[64, 74]

 Phenol

Stimulation

0.16

50 ppm

NT

[64]

 Propyl octadecanoate

Stimulation

0.43

10 ppm

NT

[66]

 Methyl dodecanoate

Deterrence

−0.92

100 ppm

NT

[47]

 Methyl (Z)-9- hexadecenoate

Deterrence

−0.86

100 ppm

NT

[47]

 Tetradecyl heptanoate

Deterrence

−0.81

10 ppm

NT

[66]

Blend of chemical compounds

 Blend of p-cresol, skatole, phenol, n-heneicosane

Stimulation

0.5

Skatole at 500 ppm, p-cresol at 100 ppm, phenol at 50 ppm, n-heneicosane at 10 ppm

NT

[64]

 Blend of nonanal, decanal, skatole

Stimulation

NM

NM

Yes

[11, 12, 31]

 Blend of nonanal, decanal, p-cresol

Stimulation

NM

NM

Yes

[11, 12, 31]

 Blend of pentadecanoic acid, myristoleic acid, myristic acid, isovaleric acid

Stimulation

0.21

1 ppm

NT

[61]

 Blend of pentadecanoic acid, myristoleic acid, myristic acid, isovaleric acid

Deterrence

−0.65

100 ppm

NT

[61]

 Blend of nonanoic acid, tetradecanoic acid and tetradecanoic acid methyl ester

Stimulation

NM

10–4 and 10–5 ppm

Yes

[32]

  1. OAI is calculated as (NT – NS)/(NT + NS), where NT and NS denote the mean number of eggs laid in the treatment and control, respectively. Positive OAI values indicate oviposition stimulation/attraction, whereas negative values indicate repellence/deterrence
  2. NT not tested, NM not mentioned
  3. aOnly the doses that elicited the most significant stimulation/attractance or deterrence/repellence are presented here