Table 1 Summary statistics for live tick numbers on dogs treated with Bravecto® or Simparica TRIO®
Tick count time1 | Treatment group | Day -2 infestation (treatment and tick counts on Day 0) | Day 21 infestation | Day 28 infestation | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | # of live ticks | # (%) tick-free dogs | N | # of live ticks | # (%) tick-free dogs | N | # of live ticks | # (%) tick-free dogs | |||||||||||
Geometric mean | Arithmetic mean | Min | Max | Geometric mean | Arithmetic mean | Min | Max | Geometric mean | Arithmetic mean | Min | Max | ||||||||
4 h | Untreated control | 8 | 23.3 | 24.0 | 17 | 38 | 0 (0.0%) | 8 | 14.0 | 15.4 | 4 | 24 | 0 (0.0%) | 8 | 15.0 | 16.1 | 6 | 26 | 0 (0.00) |
Bravecto® | 8 | 25.5 | 26.3 | 16 | 34 | 0 (0.0%) | 8 | 15.8 | 17.4 | 6 | 29 | 0 (0.0%) | 8 | 12.2 | 12.9 | 7 | 20 | 0 (0.0%) | |
Simparica TRIO® | 8 | 26.4 | 27.4 | 16 | 37 | 0 (0.0%) | 8 | 18.4 | 18.9 | 10 | 24 | 0 (0.0%) | 8 | 15.2 | 17.1 | 6 | 32 | 0 (0.0%) | |
8 h | Untreated control | 8 | 19.2 | 20.3 | 10 | 32 | 0 (0.0%) | 8 | 17.0 | 18.1 | 6 | 27 | 0 (0.0%) | 8 | 18.1 | 18.8 | 9 | 26 | 0 (0.0%) |
Bravecto® | 8 | 11.9 | 12.6 | 8 | 25 | 0 (0.0%) | 8 | 4.4 | 6.1 | 1 | 17 | 0 (0.0%) | 8 | 1.4 | 2.1 | 0 | 8 | 2 (25.0%) | |
Simparica TRIO® | 8 | 11.7 | 14.4 | 3 | 30 | 0 (0.0%) | 8 | 18.8 | 19.3 | 14 | 27 | 0 (0.0%) | 8 | 18.9 | 20.1 | 8 | 29 | 0 (0.0%) | |
12 h | Untreated control | 8 | 26.5 | 27.3 | 19 | 43 | 0 (0.0%) | 8 | 23.3 | 24.4 | 12 | 34 | 0 (0.0%) | 8 | 23.9 | 24.8 | 12 | 32 | 0 (0.0%) |
Bravecto | 8 | 0.1 | 0.1 | 0 | 1 | 7 (87.5%) | 8 | 0.2 | 0.3 | 0 | 1 | 6 (75.0%) | 8 | 0.1 | 0.1 | 0 | 1 | 7 (87.5%) | |
Simparica TRIO® | 8 | 1.8 | 5.8 | 0 | 26 | 4 (50.0%) | 8 | 14.1 | 16.4 | 5 | 26 | 0 (0.0%) | 8 | 17.3 | 19.3 | 7 | 33 | 0 (0.0%) | |
24 h | Untreated control | 8 | 27.8 | 28.4 | 22 | 40 | 0 (0.0%) | 8 | 25.7 | 26.5 | 17 | 36 | 0 (0.0%) | 8 | 27.9 | 28.5 | 19 | 40 | 0 (0.0%) |
Bravecto® | 8 | 0.0 | 0.0 | 0 | 0 | 8 (100%) | 8 | 0.0 | 0.0 | 0 | 0 | 8 (100%) | 8 | 0.0 | 0.0 | 0 | 0 | 8 (100%) | |
Simparica TRIO® | 8 | 0.1 | 0.3 | 0 | 2 | 7 (87.5%) | 8 | 0.6 | 1.0 | 0 | 5 | 5 (62.5%) | 8 | 1.0 | 1.6 | 0 | 6 | 4 (50.0%) | |