Table 1 Arithmetic (geometric) mean counts of live Ctenocephalides felis and percentage reductions after each infestation following a single treatment of dogs with fluralaner subcutaneous injection (15 mg/kg) on day 0

2

75.9 (67.8)

0.2 (0.1)

99.7 (99.8)

t₍₁₆₎ = 6.4

< 0.001

9

59.7 (57.4)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 16.7

< 0.001

16

75.9 (72.7)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 15.1

< 0.001

37^a

45.2 (41.9)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 13.2

< 0.001

65^b

46.6 (41.5)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 8.9

< 0.001

93

58.4 (52.8)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 8.5

< 0.001

128

56.1 (50.05)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 7.6

< 0.001

156

54.5 (51.8)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 12.6

< 0.001

184

45.5 (34.3)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 5.1

< 0.001

212

49.3 (45.7)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 11.2

< 0.001

247

43.8 (41.5)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 12.2

< 0.001

275

49.7 (45.4)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 9.7

< 0.001

303

44.2 (38.6)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 7.9

< 0.001

338

55.1 (48.19)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 7.0

< 0.001

367

47.9 (43.2)

0.0 (0.0)

100.0 (100.0)

t₍₁₆₎ = 8.3

< 0.001