Fig. 1 a–i

Photomicrographs of the liver sections. a Normal hepatic architecture. b–g Liver sections from the positive control group, showing marked dilatation and congestion (yellow arrow) of portal veins and hepatic sinusoids (b-d), various degrees of degenerative changes such as hydropic degeneration (yellow arrowhead) and pyknotic nuclei of hepatocytes (black arrow) (c), mild to moderate periportal inflammation and fibrosis (red arrows) (d–g), and pyemic thrombotic embolus within the portal vein (red arrowhead) (e). h Liver sections from the ivermectin (IVM)-treated rabbits, showing mild hepatic congestion and mild lymphocytic inflammation. i Nearly normal hepatic architecture in the FLR-treated group, with mild dilatation of the central vein. a–f, h, i H&E; g Masson’s trichrome