Crusted scabies in a rabbit model: a severe skin disease or more?

Parasites & Vectors

Table 1 Mean values (± SD) of serum parameters of systemic inflammation

Parameter	Group	Mean ± SD	F-test	P-value	Post hoc test
LDH (U/L)	Group I	169.84 ± 16.20	81.45	0.001***	P1	0.001***	P4	0.001***
	Group II	1311.06 ± 250.32			P2	0.856 NS	P5	0.001***
	Group III	363.28 ± 94.30			P3	0.037*	P6	0.05*
	Group IV	185.48 ± 23.54			P3	0.037*	P6	0.05*
CK-MB (U/L)	Group I	302.40 ± 21.69	31.00	0.001***	P1	0.001***	P4	0.001***
	Group II	1238.76 ± 324.76			P2	0.965 NS	P5	0.001***
	Group III	661.54 ± 136.82			P3	0.005**	P6	0.006**
	Group IV	307.46 ± 25.93			P3	0.005**	P6	0.006**
SAA (μg/ml)	Group I	3.55 ± 0.63	1418.62	0.001***	P1	0.001***	P4	0.001***
	Group II	116.39 ± 6.33			P2	0.984 NS	P5	0.001***
	Group III	6.56 ± 1.68			P3	0.171 NS	P6	0.177 NS
	Group IV	3.59 ± 0.91			P3	0.171 NS	P6	0.177 NS
CRP (μg/ml)	Group I	5.95 ± 1.34	189.68	0.001***	P1	0.001***	P4	0.001***
	Group II	85.52 ± 7.57			P2	0.796 NS	P5	0.001***
	Group III	25.11 ± 9.34			P3	0.001***	P6	0.001***
	Group IV	6.96 ± 1.33			P3	0.001***	P6	0.001***

LDH Lactate dehydrogenase, CK-MB creatine kinase myocardial band, SAA serum amyloid A, CRP C-reactive protein, Group I negative control, Group II positive control, Group III ivermectin (IVM)-treated group, Group IV fluralaner (FLR)-treated group, P1 group I and group II, P2 group I and group IV, P3 group I and group III, P4 group II and group IV, P5 group II and group III, P6 group IV and group III
NS (not significant) P > 0.05, * P < 0.05, ** P < 0.01, *** P < 0.001 (n = 10 for all groups)

ISSN: 1756-3305