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Fig. 5 | Parasites & Vectors

Fig. 5

From: csi-miR-96-5p delivered by Clonorchis sinensis extracellular vesicles promotes intrahepatic cholangiocarcinoma proliferation and migration via the ferroptosis-related PTEN/SLC7A11/GPX4 axis

Fig. 5

csi-miR-96-5p promoted ICC proliferation and migration via a ferroptosis mechanism. a Cell proliferation was measured by CCK-8 assay in vitro. b Cell proliferation was measured by tumor xenograft in vivo. c Cell migration was measured by transwell assay. d Cell GSH/GSSG radio assay. e Cell Fe2+ assay. f Cell MDA assay. g, h Cell WB assay of SLC7A11 and GPX4. ICC, intrahepatic cholangiocarcinoma; WB, western blotting; GSH, glutathione; GSSG, GSH disulfide; MDA, malondialdehyde. *P < 0.05, **P < 0.01

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