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Table 1 Contingency table and formulas for diagnostic accuracy

From: Low diagnostic performance of thick blood smears of 50 µl in comparison with direct examination of 10 µl blood and the leukoconcentration technique of 5ml blood among loiasis-suspected patients with low microfilaremia in Gabon, Central Africa, using the STARD-BLCM guidelines

 

Leukoconcentration positive

Leukoconcentration negative

Positive thick smear/direct examination

True positive (TP)

False positive (FP)

Negative thick smear/direct examination

False negative (FN)

True negative (TN)

  1. Calculations for sensitivity (Se) = TP/(TP + FN), specificity (Sp) = TN/(TN + FP), positive predictive value (PPV) = TP/(TP + FP), and negative predictive value (NPV) = TN/(TN + FN) correspond to classical formulas for the determination of performance indicators