Table 2 Correlation between the single kdr mutations S989P, V1016G and F1534C in Ae. aegypti from Ruili and Gengma counties with their resistance phenotypes to the three insecticides
Insecticide | Sampling site | Phenotypea | Number of mosquitoes tested | Single mutations | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
S989P | V1016G | F1534C | |||||||||
Frequency, N (%) | OR (95% CI) | P value (Fisher’s exact test) | Frequency, N (%) | Statistical analysis | Frequency, N (%) | OR (95% CI) | P value (Fisher’s exact test) | ||||
Permethrin (3.2%) | Ruili | R (Alive) | 57 | 42 (73.7) | 0.56 (0.11–2.86) | 0.74 | 57 (100.0) | –b | 52 (91.23) | 7.43 (1.71–32.29) | 0.01* |
S (Dead) | 12 | 10 (83.3) | 12 (100.0) | 7 (58.33) | |||||||
Gengma | R (Alive) | 33 | 28 (84.9) | _ | 0.57 | 33 (100.0) | 24 (72.73) | 5.33 (0.83–34.34) | 0.16 | ||
S (Dead) | 6 | 6 (100.0) | 6 (100.0) | 2 (33.33) | |||||||
Lambda-cyhalothrin (0.08%) | Ruili | R (Alive) | 61 | 45 (73.8) | 1.69 (0.36–7.88) | 0.80 | 61 (100.0) | 55 (90.16) | _ | 1.00 | |
S (Dead) | 8 | 5 (62.5) | 8 (100.0) | 8 (100.00) | |||||||
Gengma | R (Alive) | 60 | 48 (80.0) | 0.12 (0.0.02–0.98) | 0.046* | 60 (100.0) | 52 (86.67) | 9.29 (3.38–25.50) | 0.00* | ||
S (Dead) | 34 | 33 (97.1) | 34 (100.0) | 14 (41.18) | |||||||
Deltamethrin (0.2%) | Ruili | R (Alive) | 53 | 39 (73.6) | 0.16 (0.02–1.35) | 0.12 | 53 (100.0) | 50 (94.34) | 4.76 (0.95–23.82) | 0.12 | |
S (Dead) | 18 | 17 (94.4) | 18 (100.0) | 14 (77.78) | |||||||
Gengma | R (Alive) | 0 | 0 | _ | _ | 0 (100.0) | 0 (0.00) | _ | _ | ||
S (Dead) | 109 | 95 (87.2) | 109 (100.0) | 78 (71.56) | |||||||
Total | Ruili | R (Alive) | 171 | 126 (73.7) | 0.53 (0.21–1.34) | 0.17 | 171 (100.0) | 157 (91.81) | 3.48 (1.38–8.79) | 0.01* | |
S (Dead) | 38 | 32 (84.2) | 38 (100.0) | 29 (76.32) | |||||||
Gengma | R (Alive) | 93 | 76 (81.7) | 0.50 (0.24–1.06) | 0.07 | 93 (100.0) | 76 (81.72) | 2.62 (1.40–4.87) | 0.00* | ||
S (Dead) | 149 | 134 (89.9) | 149 (100.0) | 94 (63.09) | |||||||