Fig. 5
From: Anti-Toxoplasma gondii effect of tylosin in vitro and in vivo
Effects of tylosin on virulent or avirulent Toxoplasmos gondii infections in KM mice. Female KM mice (n = 10) were intraperitoneally infected with n = 100 RH tachyzoites (a) or n = 200 ME49 tachyzoites (b). Meanwhile, a negative control group was mock infected with sterile PBS alone. Infected mice were then treated with intraperitoneal injection of tylosin (100 mg/kg/day), oral administration of sulfadiazine sodium (SDZ, 200 mg/kg/day), tylosin + SDZ, or vehicle. The survival of mice was monitored daily