Multi-omics data elucidate parasite-host-microbiota interactions and resistance to Haemonchus contortus in sheep

Table 3 Differentially expressed genes in the abomasum between H. contortus-susceptible and resistant Morada Nova sheep using edgeR and DESeq2

Gene ID	Log FC	FDR/q-value	Gene name	Upregulated
edgeR
CCDC85B	− 8.95	0.0011	Coiled-coil domain containing 85B	Resistant
LOC121819799	− 6.67	0.0060	ncRNA	Resistant
GAST	− 13.43	0.0158	Gastrin	Resistant
LOC101121371	− 3.15	0.0257	60S ribosomal protein L37a	Resistant
LOC114116426^a	7.33	0.0004	Protein C1orf43 homolog (pseudogene)	Susceptible
LOC101116991^a	2.17	0.0060	Ribonuclease K6-like	Susceptible
LOC101104728	8.36	0.0060	Antimicrobial peptide NK-lysin	Susceptible
LOC101107420	3.98	0.0074	Phospholipase A2, membrane associated	Susceptible
GNLY	3.45	0.0141	Granulysin	Susceptible
GRP	9.09	0.0232	Gastrin releasing peptide	Susceptible
IL13	2.10	0.0474	Interleukin 13	Susceptible
DESeq2
LOC101116991^a	2.17	0.060	Ribonuclease K6-like	Susceptible
LOC114116426^a	6.81	0.055	Protein C1orf43 homolog (pseudogene)	Susceptible

ISSN: 1756-3305