Table 2 Expression change of the genes related to muscle development, myogenesis and regeneration after Trichinella infection
From: Trichinella spiralis: nurse cell formation with emphasis on analogy to muscle cell repair
Gene Name | Description | Expression change | |
|---|---|---|---|
| Â | Â | Ts | Tp a |
MyoD | skeletal muscle development and differentiation | ↑ | ↑ |
myogenin | skeletal muscle development and differentiation | ↑ | ↑ |
galectin 3 | skeletal muscle development | ↑ | ↑ |
Casitas B-lineage lymphoma (CBL) | suppressing transformation; muscle degeneration | ↑ | ↑ |
manic fringe homolog (Drosophila) (Mfng) | promoting differentiation by repression of Notch signaling | ↑ | ↑ |
eyes absent 2 homolog (Drosophila) (Eya2) | muscle development; myogenesis | ↑ | ↑ |
ski proto-oncogene; (c-ski) | cell differentiation and transformation | ↑ | ↑ |
insulin-like growth factor binding protein 4 (Igfbp4) | skeletal muscle development | ↑ | ↑ |
galectin 1 | myoblast differentiation and fusion; myotube growth | ↑ | ↑ |
dickkopf homolog 4 (Dkk4) | limb development | ↑ | ↑ |
bone morphogenetic protein 4 (Bmp4) | skeletal development; angiogenesis | ↑ | ↑ |
T-box 15 (Tbx15) | limb development of limb | ↑ | ↑ |
pre B-cell leukemia transcription factor 1 (Pbx1) | embryonic development and differentiation; | ↑ | ↑ |
numb gene homolog (Drosophila) (Numb) | cell proliferation and differentiation in muscle development | ↑ | ↑ |
paired box gene 7 (Pax7) | development; organogenesis; cell differentiation | ↑ | ↑ |
myocyte enhancer factor 2C (MEF2C) | regulation of transcription; myogenic differentiation | ↑ | ↑ |
nuclear factor of activated T cells (NFAT) | transcriptional activator activity; cytokine production | ↑ | ↑ |
deltex 1 homolog (Drosophila) (Dtx1) | myogenesis, muscle development and proliferation | ↑ | ↑ |
desmin | cytoskeleton organization; muscle contraction | ↑ | ↑ |
homeo box, msh-like 1 (Msx1) | organ morphogenesis; skeletal development | ↑ | ↑ |
myeloid leukemia factor 1 (MLF1) | cell differentiation; development; hemopoiesis | ↓ | ↓ |
chordin-like 2 (Chrdl2) | skeletal development | ↑ | NC b |
paired box gene 3 (Pax3) | cell migration and proliferation; muscle development | ↑ | NC |
Transforming growth factor 2 | controls proliferation, differentiation and transformation | ↑ | ↑ |
smad 2 | Transducer of TGF signal pathway, cell proliferation and differentiation | ↑ | NR c |
smad 4 | Transducer of TGF signal pathway, cell proliferation and differentiation | ↑ | NR |