Figure 4From: Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidasesNucleotide and deduced amino acid sequence of Ixodes ricinus cathepsin B, form 1 (IrCB). The PCR primers used are upperlined and named as in Table 1 and 2. The predicted 17 AA signal peptide is underlined, in italics. Three potential N-glycosylation sites are double underlined and the respective asparagine residues are in bold; Active site residues C113, H282, Q107and N302 are bold and shaded. Occluding loop responsible for cathepsin B exo-peptidase activity is bold, and italics.Back to article page