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Table 2 Worm and egg burdens following vaccination.

From: The nature and combination of subunits used in epitope-based Schistosoma japonicum vaccine formulations affect their efficacy

Vaccination Regimen Mean worm count ± SD Mean liver egg count ± SD Worm reduction rate (%) Liver egg reduction rate(%)
    Compared to the PBS group Compared to the 18K group Compared to the PBS group Compared to the 18K group
C2 31.33 ± 6.66 20900.9 ± 1899.84 -31.3 -34.5 10.08 3.7
C3 24.50 ± 4.23 18558.54 ± 2120.31 -2.5 -5.2 20.16* 14.5
T3 14.50 ± 8.39 10270.27 ± 4357.82 39.33** 35.80** 55.81** 51.60**
B1 23.71 ± 7.18 20308.88 ± 3154.43 0.78 0 12.62 6.5
B2 20.40 ± 6.47 21513.51 ± 4128.92 14.64 12.4 7.44 0.9
B3 18.86 ± 3.35 15366.78 ± 2371.41 22.70* 19.10* 34.81** 29.20*
C2-T3-B1 24.80 ± 6.98 19243.24 ± 2172.86 -3.8 -6.4 17.21 11.4
C2-T3-B2 18.75 ± 1.73 20000.0 ± 2167.85 21.55* 19.5* 13.95 7.9
C2-T3-B3 22.57 ± 7.14 22162.16 ± 4496.31 5.56 3.1 -2.1 4.7
C3-T3-B1 25.75 ± 6.70 18648.65 ± 4105.15 -7.7 -10.5 19.77* 14.1
C3-T3-B2 20.00 ± 6.40 12540.54 ± 4658.24 16.32 14.2 46.05** 42.2**
C3-T3-B3 21.33 ± 2.83 15855.84 ± 4944.18 10.74 8.4 31.78* 27.0*
18K 23.33 ± 6.41 21711.70 ± 3937.61 / / / /
PBS 23.88 ± 7.91 23243.24 ± 4784.20 / / / /
  1. The mean worm/liver egg burdens were calculated using results from sixteen mice from two independent experiments (n = 8). Percent protection in the two independent experiments was calculated by comparing their results with the results obtained from the 18K-PDDV and PBS groups. Results are expressed as means ± standard errors. *P < 0.05; **P < 0.01, compared to the worm/liver egg burdens of the 18K-PDDV and PBS vaccination groups.