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Figure 1 | Parasites & Vectors

Figure 1

From: Toll-like receptor activation by helminths or helminth products to alleviate inflammatory bowel disease

Figure 1

TLR induction of inflammation by parasitic infection. MyD88, TLRs and toll/IL-1 receptor domain-containing adaptor protein inducing interferon (TRIF) signal transduction is activated by helminth infection, which results in the activation of NF-κB, IRF7 and IRF3 for the induction of type I interferons (TRIF-dependent pathway). Activation of NF-κB is required for the induction of inflammatory cytokines.

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Parasites & Vectors

ISSN: 1756-3305

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