Table 3 Sensitivity, specificity and predictive value of ELISA and DDIA methods for diagnosing S. japonicum infection
Method | Sensitivity (%) | Specificity (%) | *PPV (%) | *NPV (%) | *Prevalence (%) | Reference gold standard | Author and date of publication |
|---|---|---|---|---|---|---|---|
*ELISA | 80.0 | 81.6 | 7.1 | 99.57 | 1.7 | MHT | Zhang et al. 2010 [27] |
| Â | 79.3-87.4 | 38.9-53.5 | 20.8-24.6 | 93.1-94.4 | 13.3-18.5 | two repeated KK results (6 slides) | Lin et al.2008 [13] |
| Â | 88.4-96.2 | 38.4 | 9.9-24.7 | 93.5-99.3 | 6.6-18.6 | two repeated KK results (6 slides) | Zhou et al. 2007 [14] |
| Â | 95.0 | 20.4 | 26.9 | 93.0 | 23.6 | KK (3 slides) | He et al.2007 [16] |
| Â | 98.2 | 23.8 | 37.9 | 96.6 | 32.1 | MHT | He et al. 2007 [16] |
| Â | 65.8 | 51.7 | 8.3-15.7 | 91.7-95.8 | 6.2-12.0 | combined results of KK (3 slides) and MHT | Xu et al.2007 [15] |
| Â | 65.5 | 59.4 | 12.7 | 95.0 | 8.3 | combined results of three repeated KK (12 slides) and MHT | Chen et al.2007 [34] |
| Â | 88.9-100.0 | 43.2-92.2 | 3.1-18.6 | 99.2-100.0 | 0.3-5.7 | two repeated KK results (6 slides) | Wang et al.2006 [30] |
| Â | 92.1 | 90.4 | 59.6 | 98.7 | 13.4 | MHT | Zhu et al.2005 [26] |
| Â | 83.3 | 84.3 | 77.2 | 88.8 | 3.9 | combined results of KK (3 slides) and MHT | Song et al.2003 [19] |
*DDIA | 75.0-95.5 | 37.2-78.7 | 0.5-18.4 | 98.6-99.9 | 0.4-8.2 | combined results of KK (3 slides) and MHT | Xu et et al. 2011 [38] |
| Â | 80.0 | 92.2 | 15.5 | 99.6 | 1.7 | MHT | Zhang et al. 2010 [27] |
| Â | 75.3 | 55.1 | 10.0-18.6 | 94.2-97.1 | 6.2-12.0 | combined results of KK (3 slides) and MHT | Xu et al.2007 [15] |
| Â | 95.1 | 37.4 | 41.8 | 94.2 | 32.1 | MHT | He et al.,2007 [16] |
| Â | 92.5 | 33.0 | 29.9 | 93.4 | 23.6 | KK (3 slides) | He et al.2007 [16] |
| Â | 44.8 | 69.8 | 87.6 | 21.0 | 8.3 | combined results of three repeated KK (12 slides) and MHT | Chen et al. 2007 [34] |
| Â | 96.6 | 96.3 | 80.2 | 99.5 | 13.4 | MHT | Zhu et al.2005 [26] |
| Â | 94.4 | 87.4 | 23.3 | 99.7 | 3.9 | combined results of KK (3 slides) and MHT | Song et al.2003 [19] |
| Â | 94.9 | 40.8 | 17.1 | 98.4 | 9.2 | KK (3 slides) | Li et al. 2002 [31] |