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Table 4 Efficacy results based on tick and flea count reduction as compared to the baseline counts on Day 0

From: Evaluation of the long-term efficacy and safety of an imidacloprid 10%/flumethrin 4.5% polymer matrix collar (Seresto®) in dogs and cats naturally infested with fleas and/or ticks in multicentre clinical field studies in Europe

Results

Cat study

Dog study

Efficacy **

Fleas

Ticks

Fleas

Ticks

Treatment group

IVP

CP

IVP

CP

IVP

CP

IVP

CP

SD2-4 (96 h) curative

92.9*

71.8

94.8

97.7

86.7*

66.5

79.9

86.6

month 1

99.0*

87.1

94.0

96.3

94.1

48.6

93.4*

85.2

month 2

99.7*

57.1

99.3*

90.7

98.0*

28.2

97.8*

81.4

month 3

100*

90.2

97.9*

90.0

97.4*

48.6

98.8*

81.1

month 4

99.8*

76.9

100*

96.6

99.1*

56.1

98.2*

86.9

month 5

97.4*

68.1

99.4

100

97.5*

51.0

98.8*

83.4

month 6

99.1*

63.9

99.6

96.3

99.6*

60.5

98.5

88.0

month 7

99.8*

87.4

100

100

99.9*

67.3

97.9

88.0

month 8

99.3*

87.8

99.6

100

100

69.8

91.2*

79.9

m 8 (+14 d) (SD238)

99.8*

96.1

100

100

100*

67.8

99.8

90.7

Overall

98.3*

79.3

98.4*

96.9

96.7*

57.9

94.7*

85.6

  1. *Efficacy of IVP is statistically superior to CP (p < 0.05; ANOVA adjusted for baseline or non-parametric Wilcoxon test), as evaluated from PP population**Efficacy calculations (PP population) were based on arithmetic means
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