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Table 3 Geometric mean percent adult emergence, predicted adult emergence and percent efficacy relative to non-treated controls for predicted adult flea emergence from eggs collected from cats treated with a 19.5% w/v indoxacarb topical spot-on

From: Efficacy of indoxacarb applied to cats against the adult cat flea, Ctenocephalides felis, flea eggs and adult flea emergence

  Non-treated controls1,2 Indoxacarb1,2
Study day3 % Adult emergence4 Predicted emergence5 % Adult emergence4 Predicted emergence5 Efficacy6
1 50.1a 327.9 4.6 b 10.2 96.9
2 46.1a 289.6 0.0b 0.0 100.0
3 67.0a 395.2 0.0b 0.0 100.0
9 77.1 501.8 NE 0.0 100.0
10 79.8 763.7 NE 0.0 100.0
16 75.3 345.5 NE 0.0 100.0
17 76.4 524.2 NE 0.0 100.0
23 84.3 623.2 NE 0.0 100.0
24 83.6 908.2 NE 0.0 100.0
30 77.0 436.2 NE 0.0 100.0
31 85.2a 604.0 0.0b 0.0 100.0
37 75.4a 370.2 20.0b 0.1 99.9
38 63.7a 388.6 0.0b 0.0 100.0
44 77.3a 177.5 66.1a 6.4 96.4
45 82.3a 418.1 62.5a 4.3 99.0
  1. 1 Each of 8 cats in the control group received no treatment. Each of 8 cats in the 19.5% w/v indoxacarb group were administered the topical spot-on according to label directions on Day 0.
  2. 2 Each cat was infested with 50 adult Ctenocephalides felis from the KS1 strain on days -2, 7, 14, 21, 28, 35 & 42.
  3. 3 Days post-treatment that eggs were collected.
  4. 4 % Adult emergence = (# of adults emerging/# of eggs collected) × 100.
  5. 5 Predicted emergence = (% emergence × geometric mean # eggs collected from Table 2).
  6. 6 % Efficacy = ((predicted adult emergence control-predicted adult emergence treatment)/geometric mean % adult emergence control) × 100.
  7. NE = no flea eggs collected.
  8. a,.b Values across rows with unlike superscripts are significantly different (P < 0.05).