Risk:Benefit
|
Must be very high Parasitological cure must be achieved
|
No direct associated mortality with symptomatic treatment
|
Ease of use
| |
Feasible to use at the level of a health clinic
|
Course of treatment
|
Very short course of treatment to facilitate compliance
|
Minimum acceptable treatment for children: one week (similar to antibiotics)
|
Cold chain requirements
|
Ideally not cold chain dependent
| |
Cost factors
|
Cost is less important than commitment to treatment
| |
Concomitant infections
| |
With HIV co-infection, no antimonials or monotherapies
|