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Figure 4 | Parasites & Vectors

Figure 4

From: Effects of Aedes aegypti salivary components on dendritic cell and lymphocyte biology

Figure 4

A. aegypti SGE induces lymphocyte apoptosis and cleavage of pro-caspase 3 and pro-caspase-8. Total spleen cells were incubated with Con A in medium only or in presence of A. aegypti SGE for 4 h. Annexin V staining was evaluated by flow cytometry in total cells, CD4+, CD8+ and CD19+ cells from WT mice (A) or CD4+ T cells from Bim+/− and Bim−/− mice (C). Lysates of similar cell cultures were blotted against a monoclonal antibody against pro-caspase-3 and pro-caspase-8 (B).

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