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Table 3 Transmission blocking activity: dose dependent efficacy of NeemAzal® (NA) on Plasmodium falciparum oocyst prevalence and density

From: Transmission blocking activity of Azadirachta indica and Guiera senegalensis extracts on the sporogonic development of Plasmodium falciparum field isolates in Anopheles coluzzii mosquitoes

Blood sample number Gametocytes per μL blood Treatment and concentration Prevalence of infected mosquitoes% (infected/total examined) Mean number of oocysts/mosquito (CI95)
11 400 control 64 (09/14) 51.36 (12.83-89.88)
NA 70 ppm 0 (0/25) 0.00
12 1760 control 75 (12/16) 94.38 (38.29-150.46)
NA 70 ppm 0 (00/25) 0.00
17 112 control 80 (12/15) 4.53 (2.69-6.38)
NA 60 ppm 0 (0/31) 0.00
16 184 control 64 (29/45) 4.58 (2.96-6.19)
NA 60 ppm 0 (0/56) 0.00
15 344 control 90 (09/10) 131.00 (49.69-212.31)
NA 60 ppm 12 (03/25) 0.36 (0.00-0.83)
11 400 control 68 (17/25) 49.36 (22.92-75.80)
NA 60 ppm 0 (0/25) 0.00
12 1760 control 75 (12/16) 94.38 (38.29-150.46)
NA 60 ppm 0 (0/25) 0.00
17 112 control 85 (11/13) 3.92 (1.91-5.93)
NA 50 ppm 23 (07/31) 0.35 (0.05-0.66)
16 184 control 59 (24/41) 2.68 (1.58-3.79)
NA 50 ppm 0 (0/46) 0.00
15 344 control 92 (24/26) 151.58 (97.31-205.84)
NA 50 ppm 36 (15/42) 2.29 (0.60-3.97)
11 400 control 82 (28/34) 66.50 (44.04-88.96)
NA 50 ppm 0 (0/23) 0.00
6 528 control 90 (54/60) 42.85 (31.36-54.34)
NA 50 ppm 18 (11/61) 0.30 (0.10-0.49)
17 112 control 67 (18/27) 6.56 (3.60-9.51)
NA 20 ppm 52 (12/23) 2.57 (0.86-4.27)
16 184 control 84 (38/45) 4.42 (2.92-5.93)
NA 20 ppm 41 (26/63) 0.95 (0.56-1.34)
15 344 control 81 (29/36) 92.69 (47.92-137.46)
NA 20 ppm 60 (12/20) 44.85 (7.90-81.80)
6 528 control 85 (44/52) 32.90 (22.36-43.45)
   NA 20 ppm 88 (44/50) 27.24 (19.12-35.36)