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Table 5 Adult flea emergence control after parent fleas fed on blood containing fluralaner at sub-insectcidal concentrations

From: Fluralaner, a novel isoxazoline, prevents flea (Ctenocephalides felis) reproduction in vitro and in a simulated home environment

Fluralaner (ng/mL) Adult flea emergence control (%)
Exposure daya
  3 4 5 8 9 10 Meanb
50.0 NA NA NA NA NA NA NA
25.0 NA NA NA NA NA NA NA
12.5 NA NA NA 100 NA NA 100
6.25 29.2 0 0 9.2 30.8 0 11.5
3.13 4.4 11.9 3.2 8.6 7.5 0 5.9
1.56 0 0 0 10.2 0 0 1.7
0.78 3.8 0 0 3.1 1.8 0 1.5
0.39 0 0 0 1.6 5.2 0 1.1
0.19 4.6 0 1.3 0.8 6.7 0 2.2
0.09 1.1 0.5 0 0 0 0 0.3
  1. aNo adult flea counts were performed on exposure days 6 and 7.
  2. bArithmetic mean.
  3. NA: not applicable because fleas were either killed or did not lay eggs (Table 1, Table 2, and Table 4).