Network of ITS1 haplotypes of Trichobilharzia franki from Europe. Each circle represents a single unique haplotype and the size is proportional to the number of sequences with that specific haplotype. The ITS1 shows the UK sequences to have unique haplotypes (H3 and H4), but to be most closely related to haplotypes from France (H2 and H5) with only 1 to 2 nucleotide differences separating them. There is also some evidence of gene flow between geographical locations with the same haplotype (H1 which contains HM131183, HM131179, HM131180, AJ312041, AJ312042, AY795573, AF356845) appearing in France, Switzerland and the Czech Republic. All other haplotypes appear to be country specific, H2 contains AY795572; H3 contains Ham Ra7 and Ham Ra8; H4 contains Ham Ra 6; H5 contains HM131181, HM131177, HM131184, HM131182, HM131178, HM131176; H6 contains FJ469812; H7 contains AY713969; H8 contains AY713964; H9 contains AJ312044; H10 contains AJ312045; H11 contains AY713966; H12 contains FJ469809; H13 contains FJ469808; H14 contains AJ312046; H15 contains FJ469810; H16 contains FJ469811; H17 contains AY713973; H18 contains FJ469805 and FJ469806; H19 contains FJ469814 and FJ469821; H20 contains AJ312043; H21 contains FJ469819 and FJ469820.