Figure 1
ClustalW alignment of antimicrobial peptides from Culicoides sonorensis and other insects. Deduced amino acid sequence for midge and other insect AMPs were compared and included: (A) Attacin family peptides, (B) Cecropins and (C) Defensins. Key features of each AMP are indicated in the alignment graphics: (A) Glycine-rich domains (G domains) of Attacins, (B) Conserved cationic amino acid residues (+) of Cecropins and (C) Six conserved cysteine residues (yellow) of Defensins. GenBank ID for protein sequences used in alignments were as follows: Attacins, T. yao ABX80077.1, G. morsitans morsitans CAP78961.1, D. melanogaster NP_523745.1, C. capitata XP_00451776.1, A. gambiae EAA11542.2, C. quinquefasciatus XP_001849658.1, A. aegypti EAT43734.1, C. sonorensis GAWM01008443 (attacin-like), C. sonorensis GAWM01017969 (attacin), H. cecropia AAA29183; Cecropins, C. quinquefasciatus XP_001861741.1, A. aegypti XP_001649178.1, A. albimanus ABS18287.1, C.sonorensis GAWM01000005, G. morsitans morsitans AAY41177.1, D. melanogaster AAF57026.1, M. domestica ABD38961.1, B. mori AAC60501.1; Defensins, A. gambiae ABB00948.1, A. aegypti XP_001657293.1, C. pipiens pipiens AAO38519.1, L. sericata ADI87383.1, S. peregrina P18313.1, M. domestica AAP33451.1, P. terraenovae P10891.2, G. morsitans Q8WTD4.1, C. sonorensis GAWM01019039 & GAWM01019040, A. mellifera AAA67443.1, B. terrestris ADB29129.1.